{"id":443,"date":"2017-04-20T13:28:55","date_gmt":"2017-04-20T04:28:55","guid":{"rendered":"http:\/\/www-p.hles.ocha.ac.jp\/food-iida-lab\/?page_id=443"},"modified":"2022-03-28T23:22:35","modified_gmt":"2022-03-28T14:22:35","slug":"work2","status":"publish","type":"page","link":"https:\/\/www-p.hles.ocha.ac.jp\/food-iida-lab\/work\/work2.html","title":{"rendered":"2009\u5e74\u4ee5\u524d"},"content":{"rendered":"

\u3010\u539f\u8457\u8ad6\u6587\u3011(2001-<\/strong><\/span>2009\u5e74)<\/span><\/h3>\n
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    1. Watanabe K, Okamoto F, Yokoo T,\u00a0Iida KT<\/u>, Suzuki H, Shimano H, Oshika T, Yamada N, Toyoshima H. SPARC is a major secretory gene expressed and involved in the development of proliferative diabetic retinopathy. Journal of atherosclerosis and thrombosis. 16(2):69-76, 2009<\/span><\/li>\n
    2. \u4eca\u4e95\u667a\u5b50\u3001\u6e05\u6c34\u548c\u5f18\u3001\u5742\u6238\u6d0b\u5b50\u3001\u98ef\u7530\u85ab\u5b50<\/u>\u3001\u4e45\u91ce\u8b5c\u4e5f\u3001\u4eca\u5ddd\u91cd\u5f66\u3001\u76ee\u5d0e\u767b\u3001\u6cb3\u91ce\u4e00\u90ce:\u30a8\u30a2\u30ed\u30d3\u30c3\u30af\u904b\u52d5\u3068\u30ec\u30b8\u30b9\u30bf\u30f3\u30b9\u904b\u52d5\u306e\u8907\u5408\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u304c\u9ad8\u9f62\u5973\u6027\u306e\u30a2\u30c7\u30a3\u30dd\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306b\u4e0e\u3048\u308b\u5f71\u97ff. \u65e5\u672c\u81e8\u5e8a\u30b9\u30dd\u30fc\u30c4\u533b\u5b66\u4f1a\u8a8c. 17\u5dfb2\u53f7\u3001283-289\u9801\u30012009<\/span><\/li>\n
    3. \u4eca\u4e95\u667a\u5b50\u3001\u76f8\u6fa4\u52dd\u6cbb\u3001\u6731\u7f8e\u8ce2\u3001\u98ef\u7530\u85ab\u5b50<\/u>\u3001\u6751\u4e95\u6587\u6c5f\u3001\u6cb3\u91ce\u4e00\u90ce\u3001\u4eca\u5ddd\u91cd\u5f66\u3001\u76ee\u5d0e\u767b:\u4e00\u904e\u6027\u30ec\u30b8\u30b9\u30bf\u30f3\u30b9\u904b\u52d5\u306b\u304a\u3051\u308b\u30a2\u30c7\u30a3\u30dd\u30cd\u30af\u30c1\u30f3\u3001\u30ec\u30d7\u30c1\u30f3\u306e\u5fdc\u7b54. \u4f53\u529b\u79d1\u5b66(\u65e5\u672c\u4f53\u529b\u533b\u5b66\u4f1a\u96d1\u8a8c). 239-246\u9801\u300158\u5dfb2\u53f7\u30012009<\/span><\/li>\n
    4. Hooper AT, Butler JM, Nolan DJ, Kranz A,\u00a0Iida K<\/u>, Kobayashi M, Kopp HG, Shido K, Petit I, Yanger K, James D, Witte L, Zhu Z, Wu Y, Pytowski B, Rosenwaks Z, Mittal V, Sato TN, Rafii S. Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells. Cell Stem Cell. 4(3):263-74, 2009.<\/span><\/li>\n
    5. Huang H,\u00a0Iida K<\/u>, Murakami H, Saito Y, Otsuki T, Iemitsu M, Maeda S, Sone H, Kuno S, Ajisaka R. Influence of adiponectin gene polymorphism SNP276 (G\/T) on adiponectin in response to exercise training. Endocrine Journal. 54(6):879-886. 2007.<\/span><\/li>\n
    6. Ohgaki S,\u00a0Iida K<\/u>, Yokoo T, Watanabe K, Kihara R, Suzuki H, Shimano H, Toyoshima H, Yamada N. Identification of ISG12b as a putative interferon-inducible adipocytokine which is highly expressed in white adipose tissue. Journal of Atherosclerosis and Thrombosis. 14(4):179-184. 2007.<\/span><\/li>\n
    7. Huang H,\u00a0Iida KT<\/u>, Sone H, Ajisaka R. The regulation of adiponectin receptors expression by acute exercise in mice. Experimental and Clinical Endocrinology & Diabetes. 115(7):417-422. 2007.<\/span><\/li>\n
    8. Huang H,\u00a0Iida KT<\/u>, Sone H, Yokoo T, Yamada N, Ajisaka R. The effect of exercise training on adiponectin receptor expression in KKAy obese\/diabetic mice. The Journal of Endocrinology. 189(3):643-53. 2006.<\/span><\/li>\n
    9. Suzuki M, Kakuta H, Takahashi A, Shimano H, Iida KT<\/u>, Yokoo T, Kihara R, Yamada N. Effects of atorvastatin on glucose metabolism and insulin resistance in KK\/Ay mice. J Atheroscler Thromb. 12(2):77-84. 2005<\/span><\/li>\n
    10. Wang Y, Suzuki H, Yokoo T,\u00a0Iida KT<\/u>, Kihara R, Miura M, Watanabe K, Sone H, Shimano H, Toyoshima H, Yamada N. WGEF is a novel RhoGEF expressed in intestine, liver, heart, and kidney. Biochemical and biophysical research communications 324(3):1053-8. 2004<\/span><\/li>\n
    11. Sone H, Shimano H, Shu M, Nakakuki M, Takahashi A, Sakai M, Sakamoto Y, Yokoo T, Matsuzaka K, Okazaki H, Nakagawa Y,\u00a0Iida KT<\/u>, Suzuki H, Toyoshima H, Horiuchi S, Yamada N. Statins downregulate ATP-binding-cassette transporter A1 gene expression in macrophages. Biochemical and biophysical research communications. 316(3):790-4. 2004<\/span><\/li>\n
    12. Yokoo T, Toyoshima H, Miura M, Wang Y,\u00a0Iida KT<\/u>, Suzuki H, Sone H, Shimano H, Gotoda T, Nishimori S, Tanaka K, Yamada N. p57Kip2 regulates actin dynamics by binding and translocating LIM-kinase 1 to the nucleus. The Journal of biological chemistry. 278(52):52919-23. 2003.<\/span><\/li>\n
    13. Iida KT<\/u>, Kawakami Y, Suzuki M, Shimano H, Toyoshima H, Sone H, Shimada K, Iwama Y, Watanabe Y, Mokuno H, Kamata K, Yamada N. Effect of thiazolidinediones and metformin on LDL oxidation and aortic endothelium relaxation in diabetic GK rats. American journal of physiology. Endocrinology and metabolism. 284(6):E1125-30. 2003.<\/span><\/li>\n
    14. Sone H, Shimano H, Ebinuma H, Takahashi A, Yano Y,\u00a0Iida KT<\/u>, Suzuki H, Toyoshima H, Kawakami Y, Okuda Y, Noguchi Y, Ushizawa K, Saito K, Yamada N. Physiological changes in circulating mannose levels in normal, glucose-intolerant, and diabetic subjects. Metabolism. 52(8):1019-27. 2003<\/span><\/li>\n
    15. Iida K<\/u>, Kawakami Y, Sone H, Suzuki H, Yatoh S, Isobe K, Takekoshi K, Yamada N. Vascular endothelial growth factor gene expression in a retinal pigmented cell is up-regulated by glucose deprivation through 3′ UTR. Life Sciences. 71(14):1607-14. 2002<\/span><\/li>\n
    16. Iida KT<\/u>, Kawakami Y, Suzuki H, Sone H, Shimano H, Toyoshima H, Okuda Y, Yamada N. PPAR gamma ligands, troglitazone and pioglitazone, up-regulate expression of HMG-CoA synthase and HMG-CoA reductase gene in THP-1 macrophages. FEBS Letters. 520(1-3): 177-81. 2002.<\/span><\/li>\n
    17. Iida KT<\/u>, Suzuki H, Sone H, Shimano H, Toyoshima H, Yatoh S, Asano T, Okuda Y, Yamada N. Insulin inhibits apoptosis of macrophage cell line, THP-1 cells, via phosphatidylinositol-3-kinase-dependent pathway. Arteriosclerosis thrombosis and vascular biology. 22(3):380-6. 2002<\/span><\/li>\n
    18. Sone H, Shimano H, Sakakura Y, Inoue N, Amemiya-Kudo M, Yahagi N, Osawa M, Suzuki H, Yokoo T, Takahashi A,\u00a0Iida K<\/u>, Toyoshima H, Iwama A, Yamada N. Acetyl-coenzyme A synthetase is a lipogenic enzyme controlled by SREBP-1 and energy status. American journal of physiology. Endocrinology and metabolism. 282(1):E222-30. 2002<\/span><\/li>\n
    19. Sone H, Sakauchi M, Takahashi A, Suzuki H, Inoue N,\u00a0Iida K<\/u>, Shimano H, Toyoshima H, Kawakami Y, Okuda Y, Matsuo K, Yamada N. Elevated levels of vascular endothelial growth factor in the sera of patients with rheumatoid arthritis correlation with disease activity. Life Sciences. 69(16):1861-9. 2001<\/span><\/li>\n
    20. Iida KT<\/u>, Shimano H, Kawakami Y, Sone H, Toyoshima H, Suzuki S, Asano T, Okuda Y, Yamada N. Insulin up-regulates tumor necrosis factor-alpha production in macrophages through an extracellular-regulated kinase-dependent pathway. The Journal of biological chemistry. 276(35):32531-7. 2001.<\/span><\/li>\n
    21. Sone H, Takahashi A,\u00a0Iida K<\/u>, Yamada N. Disease model: hyperinsulinemia and insulin resistance. Part B–polygenic and other animal models. Trends in molecular medicine. 7(8):373-6. 2001<\/span><\/li>\n<\/ol>\n<\/li>\n<\/ul>\n

      \u3010\u8457\u66f8\u30fb\u8a33\u66f8 \u307b\u304b\u3011(2001-2009\u5e74)<\/span><\/span><\/strong><\/span><\/h3>\n